25-OH Vitamin D3 Biotin Conjugate

<strong>25-OH Vitamin D3 Biotin Conjugate</strong>_x000D_ <strong>Catalog number:</strong> B2010192_x000D_ <strong>Lot number:</strong> Batch Dependent_x000D_ <strong>Expiration Date:</strong> Batch dependent_x000D_ <strong>Amount:</strong> 1 mg_x000D_ <strong>Molecular Weight</strong>: 797 g/mol_x000D_ <strong>Appearance:</strong> Solution_x000D_ <strong>Concentration</strong>: 1 mg/mL in DMSO (resuspend first in 100% Ethanol or other buffers to working concentrations, not directly soluble in water)_x000D_ <strong>Purity</strong>: &gt;97%_x000D_ _x000D_ <strong>Applications:</strong> 25-OH Vitamin D3 conjugated to Biotin via a 22 A spacer arm. The spacer adds flexibility to the 25-OH Vitamin D3 moiety which is required for its interaction with specific antibodies and other binding partners. This compound has been validated for use in many 25-OH Vitamin D applications including ELISA._x000D_ <strong>Storage:</strong> -20°C_x000D_ <strong>Keywords:</strong> 25-OH Vitamin D3-LC-Biotin, 25-OH Vitamin D3 LC-Biotin, Synthetic 25-OH Vitamin D3 LC Biotin, 25-OH Vitamin D3-LC-Biotin, Synthetic 25-OH Vitamin D3 LC-Biotin, Human Synthetic 25-OH Vitamin D3 LC Biotin, N-(3-(((1S,Z)-3-(2-((1R,7aR,E)-1-((R)-6-hydroxy-6-methylheptan-2-yl)-7a-methylhexahydro-1H-inden-4(2H)-ylidene)ethylidene)-4-methylenecyclohexyl)oxy)propyl)-6-(5-(2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)pentanamido)hexanamide_x000D_ <strong>Grade:</strong> Biotechnology grade. All components are highly pure (minimum 99%). All solutions are made with Type I ultrapure water (resistivity &gt;18 MΩ-cm) and are filtered on a 0.22 um._x000D_ _x000D_ <strong>References:</strong>_x000D_ 1: Holick MF, Smith E, Pincus S. Skin as the site of vitamin D synthesis and_x000D_ target tissue for 1,25-dihydroxyvitamin D3. Use of calcitriol_x000D_ (1,25-dihydroxyvitamin D3) for treatment of psoriasis. Arch Dermatol. 1987_x000D_ Dec;123(12):1677-1683a._x000D_ _x000D_ 2: Guo J, Lovegrove JA, Givens DI. 25(OH)D3-enriched or fortified foods are more_x000D_ efficient at tackling inadequate vitamin D status than vitamin D3. Proc Nutr_x000D_ Soc. 2018 Aug;77(3):282-291. doi: 10.1017/S0029665117004062._x000D_ _x000D_ 3: Hassan AB, Hozayen RF, Alotaibi RA, Tayem YI. Therapeutic and maintenance_x000D_ regimens of vitamin D3 supplementation in healthy adults: A systematic review._x000D_ Cell Mol Biol (Noisy-le-grand). 2018 Nov 30;64(14):8-14._x000D_ _x000D_ 4: McCullough PJ, Lehrer DS, Amend J. Daily oral dosing of vitamin D3 using 5000_x000D_ TO 50,000 international units a day in long-term hospitalized patients: Insights_x000D_ from a seven year experience. J Steroid Biochem Mol Biol. 2019 May;189:228-239._x000D_ _x000D_ 5: Rosendahl J, Valkama S, Holmlund-Suila E, Enlund-Cerullo M, Hauta-Alus H,_x000D_ Helve O, Hytinantti T, Levälahti E, Kajantie E, Viljakainen H, Mäkitie O,_x000D_ Andersson S. Effect of Higher vs Standard Dosage of Vitamin D3 Supplementation_x000D_ on Bone Strength and Infection in Healthy Infants: A Randomized Clinical Trial._x000D_ JAMA Pediatr. 2018 Jul 1;172(7):646-654._x000D_ _x000D_ 6: Penagini F, Borsani B, Maruca K, Giosia V, Bova S, Mastrangelo M, Zuccotti_x000D_ GV, Mora S. Short-Term Vitamin D3 Supplementation in Children with_x000D_ Neurodisabilities: Comparison of Two Delivery Methods. <a href="https://pubmed.ncbi.nlm.nih.gov/28898870/">Horm Res Paediatr</a>. 2017;88(3-4):281-284._x000D_ _x000D_ <strong>Products Related to 25-OH Vitamin D3 Biotin Conjugate</strong><a>: Biochemical Buffers and Solutions</a>