S32212
S32212 is a serotonin type 2C receptor inverse agonist and an 2 adrenoceptor antagonist. S32212 exhibits antidepressant activity and can reduce immobility time in forced-swim test in rats[1].
Product Specifications
CAS Number
847968-58-5
UNSPSC
12352005
Target
Adrenergic Receptor
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Smiles
O=C(N1CCC2=C1C=CC3=CC=CC=C23)NC4=CC=C(OC)C(N5CCN(C)CC5)=C4
Molecular Formula
C25H28N4O2
Molecular Weight
416.52
References & Citations
[1]Dekeyne, A., et al., (2012) . S32212, a novel serotonin type 2C receptor inverse agonist/α2-adrenoceptor antagonist and potential antidepressant: II. A behavioral, neurochemical, and electrophysiological characterization. The Journal of pharmacology and experimental therapeutics, 340 (3), 765-780. |[2]Dekeyne, A., et al., (2012) . S32212, a novel serotonin type 2C receptor inverse agonist/α2-adrenoceptor antagonist and potential antidepressant: II. A behavioral, neurochemical, and electrophysiological characterization. The Journal of pharmacology and experimental therapeutics, 340 (3), 765-780.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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