S32212

S32212 is a serotonin type 2C receptor inverse agonist and an 2 adrenoceptor antagonist. S32212 exhibits antidepressant activity and can reduce immobility time in forced-swim test in rats[1].

Product Specifications

CAS Number

[847968-58-5]

UNSPSC

12352005

Target

Adrenergic Receptor

Related Pathways

GPCR/G Protein; Neuronal Signaling

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Smiles

O=C(N1CCC2=C1C=CC3=CC=CC=C23)NC4=CC=C(OC)C(N5CCN(C)CC5)=C4

Molecular Formula

C25H28N4O2

Molecular Weight

416.52

References & Citations

[1]Dekeyne, A., et al., (2012) . S32212, a novel serotonin type 2C receptor inverse agonist/α2-adrenoceptor antagonist and potential antidepressant: II. A behavioral, neurochemical, and electrophysiological characterization. The Journal of pharmacology and experimental therapeutics, 340 (3), 765-780. |[2]Dekeyne, A., et al., (2012) . S32212, a novel serotonin type 2C receptor inverse agonist/α2-adrenoceptor antagonist and potential antidepressant: II. A behavioral, neurochemical, and electrophysiological characterization. The Journal of pharmacology and experimental therapeutics, 340 (3), 765-780.