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MOG Antibody

Product Specifications

Background

The product of this gene is a membrane protein expressed on the oligodendrocyte cell surface and the outermost surface of myelin sheaths. Due to this localization, it is a primary target antigen involved in immune-mediated demyelination. This protein may be involved in completion and maintenance of the myelin sheath and in cell-cell communication. Alternatively spliced transcript variants encoding different isoforms have been identified.

NCBI Gene ID

4340

Swiss Prot

Q16653

Accession Number

Q16653

Host

Rabbit

Reactivity

Human

Immunogen

This MOG antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 82-109 amino acids from the Central region of human MOG.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Neuroscience

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Monkey

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Product Datasheet

https://www.prosci-inc.com/?datasheet_sku=59-661

Calculated Molecular Weight

28 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

MOG

NCBI Official Name

Myelin-oligodendrocyte glycoprotein

NCBI Organism

Homo sapiens

Background Reference 01

Bailey, S.D., et al. Diabetes Care 33 (10) :2250-2253 (2010)

Background Reference 02

Boyle, L.H., et al. J. Neurochem. 102 (6) :1853-1862 (2007)

Background Reference 03

Allamargot, C., et al. J. Neurochem. 101 (2) :298-312 (2007)

Background Reference 04

Delarasse, C., et al. J. Neurochem. 98 (6) :1707-1717 (2006)

Other Product Names

Myelin-oligodendrocyte glycoprotein, MOG

Tested Applications

WB

Protein ID

317373391

Physical Properties

Liquid

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