6-Nitroquipazine

6-Nitroquipazine (DU24565) is a potent and selective 5-HT transporter inhibitor, with a Ki of 0.17 nM. 6-Nitroquipazine can be used in the research of psychiatric disorders such as depression[1].

Product Specifications

CAS Number

[77372-73-7]

Product Name Alternative

DU24565

UNSPSC

12352005

Hazard Statement

H302-H315-H319-H335

Target

Serotonin Transporter

Related Pathways

Neuronal Signaling

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Smiles

O=[N+](C1=CC=C2N=C(N3CCNCC3)C=CC2=C1)[O-]

Molecular Formula

C13H14N4O2

Molecular Weight

258.28

Precautions

P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

References & Citations

[1]Lee BS, et al. Syntheses and binding affinities of 6-nitroquipazine analogues for serotonin transporter: Part 3. A potential 5-HT transporter imaging agent, 3- (3-[18F]fluoropropyl) -6-nitroquipazine. Bioorg Med Chem. 2003 Nov 17;11 (23) :4949-58.