Eicosatetraynoic acid
Eicosatetraynoic acid (ETYA) is a nonspecific inhibitor of cyclooxygenase and lipoxygenase (ID50=8 μM and 4 μM, respectively) [1]. Eicosatetraynoic acid (ETYA) activates PPARα and PPARγ chimeras at 10 μM[2]. Eicosatetraynoic acid specifically interferes with the replication of the cowpox virus both in vivo and in vitro[3]. Eicosatetraynoic acid is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
Product Specifications
CAS Number
1191-85-1
Product Name Alternative
ETYA
UNSPSC
12352211
Target
COX; Orthopoxvirus; PPAR
Related Pathways
Anti-infection; Cell Cycle/DNA Damage; Immunology/Inflammation; Metabolic Enzyme/Protease; Vitamin D Related/Nuclear Receptor
Field of Research
Others
Purity
99.9
Solubility
DMSO : 2 mg/mL (ultrasonic) |Ethanol : < 1 mg/mL
Smiles
CCCCCC#CCC#CCC#CCC#CCCCC(O)=O
Molecular Formula
C20H24O2
Molecular Weight
296.40
References & Citations
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
COX
Frequently Asked Questions
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