Pexacerfont (Standard)

Pexacerfont (Standard) is the analytical standard of Pexacerfont. This product is intended for research and analytical applications. Pexacerfont is a selective corticotropin-releasing factor (CRF1) receptor antagonist with IC50 of 6.1±0.6 nM for human CRF1 receptor.

Product Specifications

CAS Number

[459856-18-9]

UNSPSC

12352100

Target

CRFR; Reference Standards

Related Pathways

GPCR/G Protein; Others

Field of Research

Neurological Disease; Endocrinology

Smiles

CC[C@H](NC1=NC(C)=NC2=C(C3=CC=C(OC)N=C3C)C(C)=NN21)C

Molecular Formula

C18H24N6O

Molecular Weight

340.42

References & Citations

[1]Zhou L, et al. In vitro and in vivo metabolism and pharmacokinetics of BMS-562086, a potent and orally bioavailable corticotropin-releasing factor-1 receptor antagonist. Drug Metab Dispos. 2012 Jun;40 (6) :1093-103.