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Diclofop

Diclofop (Dichlorfop acid) is an acetyl-CoA carboxylase (ACC) inhibitor. Diclofop is also the major metabolite of the herbicide Diclofop-methyl (HY-136367) . Diclofop exhibits antimalarial activity with an IC50 of 210 μM against P. falciparum[1][2].

Product Specifications

CAS Number

[40843-25-2]

Product Name Alternative

Dichlorfop acid; (±) -Diclofop

UNSPSC

12352005

Hazard Statement

H302-H315-H319-H335

Target

Drug Metabolite; Parasite

Related Pathways

Anti-infection; Metabolic Enzyme/Protease

Field of Research

Infection

Smiles

O=C(C(C)OC1=CC=C(C=C1)OC2=CC=C(C=C2Cl)Cl)O

Molecular Formula

C15H12Cl2O4

Molecular Weight

327.16

Precautions

P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

References & Citations

[1]Wiesner J, et al. The plastid-like organelle of apicomplexan parasites as drug target. Curr Pharm Des. 2008;14 (9) :855-71.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Curated Selection

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