TD-6450
TD-6450 (Compound 51) is an orally active HCV 1A inhibitor. TD-6450 inhibits the pan-genotypic nonstructural protein 5A (NS5A) . TD-6450 can be used for research on diseases such as hepatitis[1].
Product Specifications
CAS Number
[1374883-22-3]
UNSPSC
12352005
Target
HCV
Related Pathways
Anti-infection
Field of Research
Infection
Smiles
COC(N[C@@H](C(C)C)C(N1[C@H](C(N2)=NC=C2C(C=C3)=CC=C3C4=C(OC(F)(F)F)C=C(NC(C5=CN=C(C=C5)N6C[C@@H](N(C[C@H]6C)C(NC)=O)C)=O)C=C4)CCC1)=O)=O
Molecular Formula
C41H48F3N9O6
Molecular Weight
819.87
References & Citations
[1]Belema M, et al. Discovery and development of hepatitis C virus NS5A replication complex inhibitors. J Med Chem. 2014 Mar 13;57 (5) :1643-72. |[2]Carucci M, et al. Safe drugs with high potential to block malaria transmission revealed by a spleen-mimetic screening. Nat Commun. 2023 Apr 7;14 (1) :1951.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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