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TD-6450

TD-6450 (Compound 51) is an orally active HCV 1A inhibitor. TD-6450 inhibits the pan-genotypic nonstructural protein 5A (NS5A) . TD-6450 can be used for research on diseases such as hepatitis[1].

Product Specifications

CAS Number

1374883-22-3

UNSPSC

12352005

Target

HCV

Related Pathways

Anti-infection

Field of Research

Infection

Smiles

COC(N[C@@H](C(C)C)C(N1[C@H](C(N2)=NC=C2C(C=C3)=CC=C3C4=C(OC(F)(F)F)C=C(NC(C5=CN=C(C=C5)N6C[C@@H](N(C[C@H]6C)C(NC)=O)C)=O)C=C4)CCC1)=O)=O

Molecular Formula

C41H48F3N9O6

Molecular Weight

819.87

References & Citations

[1]Belema M, et al. Discovery and development of hepatitis C virus NS5A replication complex inhibitors. J Med Chem. 2014 Mar 13;57 (5) :1643-72. |[2]Carucci M, et al. Safe drugs with high potential to block malaria transmission revealed by a spleen-mimetic screening. Nat Commun. 2023 Apr 7;14 (1) :1951.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Frequently Asked Questions

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