AD-5075
AD-5075 is an orally active insulin sensitizer. AD-5075 mediates its antidiabetic activity by binding to PPARγ and thereby generating an active conformation of the receptor[1].
Product Specifications
CAS Number
103788-05-2
UNSPSC
12352005
Target
PPAR
Related Pathways
Cell Cycle/DNA Damage; Metabolic Enzyme/Protease; Vitamin D Related/Nuclear Receptor
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Metabolic Disease
Smiles
O=C(SC1CC2=CC=C(C=C2)OCC(C3=C(OC(C4=CC=CC=C4)=N3)C)O)NC1=O
Molecular Formula
C22H20N2O5S
Molecular Weight
424.47
References & Citations
[1]Berger J, et al. Thiazolidinediones produce a conformational change in peroxisomal proliferator-activated receptor-gamma: binding and activation correlate with antidiabetic actions in db/db mice[J]. Endocrinology, 1996, 137 (10) : 4189-4195.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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