Dasabuvir sodium
Product Specifications
CAS Number
1132940-11-4
Target
Others, DNA/RNA Synthesis, HCV Protease
Related Pathways
Proteases/Proteasome, Cell Cycle/Checkpoint, Others, Microbiology/Virology, DNA Damage/DNA Repair
Bioactivity
Dasabuvir (ABT-333) sodium is a non-nucleoside hepatitis C virus (HCV) polymerase inhibitor that exhibits inhibition of the RNA-dependent RNA polymerase (RNA polymerase) encoded by the HCV NS5B gene. Dasabuvir sodium inhibited genotype 1a (strain H77) replicon (EC50: 7.7 nM) and 1b (strain Con1) replicon (EC50: 1.8 nM) .
Smiles
[Na+].COc1c(cc(cc1C(C)(C)C)-n1ccc(=O)[nH]c1=O)-c1ccc2cc([N-]S(C)(=O)=O)ccc2c1
Molecular Formula
C26H26N3NaO5S
Molecular Weight
515.56
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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