Licarbazepine-d8

Licarbazepine-d8 (BIA 2-005-d8) is deuterium labeled Licarbazepine. Licarbazepine (BIA 2-005; GP 47779) ?is a?voltage-gated sodium channel?blocker?with?anticonvulsant?and?mood-stabilizing?effects[1].

Product Specifications

CAS Number

[1261393-17-2]

Product Name Alternative

BIA 2-005-d8; GP 47779-d8

UNSPSC

12352005

Target

Isotope-Labeled Compounds; Sodium Channel

Related Pathways

Membrane Transporter/Ion Channel; Others

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Smiles

NC(N1C2=C([2H])C([2H])=C([2H])C=C2C(C([2H])([2H])C3=CC([2H])=C([2H])C([2H])=C31)O)=O

Molecular Formula

C15H6D8N2O2

Molecular Weight

262.33

References & Citations

[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53 (2) :211-216.|[2]Rajinder P Singh, et al. A review of eslicarbazepine acetate for the adjunctive treatment of partial-onset epilepsy. J Cent Nerv Syst Dis. 2011 Jul 20;3:179-87.