Y 27632
ROCK kinase inhibitor
Product Specifications
Background
Y 27632 is a very potent and selective ROCK1 and ROCK2 inhibitor. Y 27632 is cell permeable and is an ATP competitive inhibitor.
CAS Number
146986-50-7
Product Name Alternative
Y-27632 dihydrochloride, (R) - (+) -trans-N- (4-Pyridyl) -4- (1-aminoethyl) -cyclohexanecarboxamide . 2HCl
UNSPSC
41116105
Type
Inhibitor
Source
Synthetic
Field of Research
Cell Signaling | Cancer | Apoptosis | Cancer Growth Inhibitors | Tyrosine Kinase Inhibitors
Purity
≥98% (HPLC)
Weight
0.005
Format
White to pale yellow powder
Solubility
Soluble in DMSO (25 mg/ml), methanol (25 mg/ml), acetonitrile (<1 mg/ml), dioxan (<1 mg/ml), water (very soluble
Molecular Formula
C14H23Cl2N3O
Molecular Weight
320.3
Precautions
Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.
References & Citations
1. Shi J., et al. (2013) Cell Death & Disease, 4: e483.
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