E 3040
E 3040 is an orally active dual inhibitor of 5-lipoxygenase and thromboxane synthase. E 3040 exhibits anti-inflammatory effect[1].
Product Specifications
CAS Number
[145096-30-6]
UNSPSC
12352005
Target
Lipoxygenase; Prostaglandin Receptor
Related Pathways
GPCR/G Protein; Metabolic Enzyme/Protease
Field of Research
Inflammation/Immunology
Smiles
OC1=C(C)C(CC2=CC=CN=C2)=C3N=C(NC)SC3=C1C
Molecular Formula
C16H17N3OS
Molecular Weight
299.39
References & Citations
[1]Oketani K, et al. Effect of E3040, an inhibitor of 5-lipoxygenase and thromboxane synthase, on rat bowel damage induced by lipopolysaccharide. Eur J Pharmacol. 2001 Sep 14;427 (2) :159-66.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
Phase 2
Isoform
5-LOX
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