UR-12947
UR-12947 is a platelet glycoprotein (GP) IIb-IIIa antagonist. UR-12947 exhibits potent inhibitory activity against platelet aggregation in human platelet-rich plasma, with an IC50 value of 3.5 nM. UR-12947 can be used in the research of arterial thrombotic diseases[1].
Product Specifications
CAS Number
718595-27-8
UNSPSC
12352005
Target
Integrin
Related Pathways
Cytoskeleton
Field of Research
Cardiovascular Disease
Smiles
O=S(N[C@H](C(O)=O)CNC(C1=C(C(C)C)N=C(N2CCC(C3CCNCC3)CC2)S1)=O)(C4=CC=CC=C4)=O
Molecular Formula
C26H37N5O5S2
Molecular Weight
563.73
References & Citations
[1]Scarborough RM, et al. Platelet glycoprotein IIb-IIIa antagonists as prototypical integrin blockers: novel parenteral and potential oral antithrombotic agents. J Med Chem. 2000 Sep 21;43 (19) :3453-73.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
orb3077896 100 µg
Caspase-8/CASP8 Rabbit Polyclonal Antibody (Fluoro647)
Sign In for Pricing
View Details