MLi-2 (Standard)
MLi-2 (Standard) is the analytical standard of MLi-2. This product is intended for research and analytical applications. MLi-2, a chemical probe, is an orally active and highly selective LRRK2 inhibitor with an IC50 of 0.76 nM. MLi-2 has the potential for Parkinson’s disease[1].
Product Specifications
CAS Number
1627091-47-7
Target
LRRK2; Reference Standards
Related Pathways
Autophagy; Others
Field of Research
Neurological Disease
Smiles
C[C@@](C1)([H])O[C@](C)([H])CN1C2=CC(C3=NNC4=CC=C(OC5(C)CC5)C=C43)=NC=N2
Molecular Formula
C21H25N5O2
Molecular Weight
379.46
References & Citations
[1]Fell MJ, et al. MLi-2, a Potent, Selective, and Centrally Active Compound for Exploring the Therapeutic Potential and Safety of LRRK2 Kinase Inhibition. J Pharmacol Exp Ther. 2015 Dec;355 (3) :397-409.
Shipping Conditions
Room temperature
Scientific Category
Reference Standards
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