HT1376 SMAD/TGFbeta Reporter (Luc) stable cell line

HT1376 SMAD/TGFbeta Reporter (Luc) cells are derived from the human HT1376 urinary bladder carcinoma cell line by stably integration of a SMAD/TGFbeta firefly luciferase reporter construct. HT1376 cell line has been widely used to study bladder cancer biology, test potential treatments, and explore the molecular mechanisms underlying the disease. HT1376 SMAD/TGFbeta Reporter (Luc) cells stably express firefly luciferase under the control of the SMAD/TGFbeta response elements, can be used for monitoring the activity of TGF?/SMAD signaling pathway.