Eotaxin/CCL11, Human

Eotaxin/CCL11 Protein, Human is a potent chemoattractant for eosinophil cells and provides a new mechanism to explain tissue eosinophilia.

Product Specifications

Product Name Alternative

Eotaxin/CCL11 Protein, Human, Human, E. coli

UNSPSC

12352202

Type

Recombinant Proteins

Assay Protocol

https://www.medchemexpress.com/cytokines/eotaxin-ccl11-protein-human.html

Purity

97.0

Smiles

GPASVPTTCCFNLANRKIPLQRLESYRRITSGKCPQKAVIFKTKLAKDICADPKKKWVQDSMKYLDQKSPTPKP

Molecular Formula

6356 (Gene_ID) P51671 (G24-P97) (Accession)

Molecular Weight

Approximately 10 kDa, based on SDS-PAGE under reducing conditions.

References & Citations

[1]Garcia-Zepeda EA, et al. Human eotaxin is a specific chemoattractant for eosinophil cells and provides a new mechanism to explain tissue eosinophilia. Nat Med. 1996 Apr;2 (4) :449-56.|[2]Salcedo R, et al. Eotaxin (CCL11) induces in vivo angiogenic responses by human CCR3+ endothelial cells. J Immunol. 2001 Jun 15;166 (12) :7571-8.|[3]Antonio L. Teixeira, et al. Revisiting the Role of Eotaxin-1/CCL11 in Psychiatric Disorders. Front Psychiatry. 2018 Jun 14;9:241.|[4]R Salcedo, et al. Eotaxin (CCL11) induces in vivo angiogenic responses by human CCR3+ endothelial cells. J Immunol. 2001 Jun 15;166 (12) :7571-8.|[5]Sara S Cheng, et al. Eotaxin/CCL11 is a negative regulator of neutrophil recruitment in a murine model of endotoxemia.Exp Mol Pathol. 2002 Aug;73 (1) :1-8.