Glutaminyl Cyclase Inhibitor 6
Product Specifications
UNSPSC Description
Glutaminyl Cyclase Inhibitor 6 (compound BI-43) is a secretory glutaminyl cyclase (sQC) and golgi-resident glutaminyl cyclase (gQC) inhibitor with IC50 values of 0.012 0.040 µM, respectively. Glutaminyl Cyclase Inhibitor 6 has the potential for the research of Parkinson’s disease[1].
Target Antigen
Amyloid-β
Type
Reference compound
Related Pathways
Neuronal Signaling
Applications
Neuroscience-Neurodegeneration
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/glutaminyl-cyclase-inhibitor-6.html
Smiles
O=C(/C1=C\C2=CC3=C(C=C2)NC=N3)NC4=C1C(OC5CCN(CC5)C(C6=CC=NC=C6)=O)=CC=C4
Molecular Weight
465.50
References & Citations
[1]Mou J, et al. X-ray Structure-Guided Discovery of a Potent Benzimidazole Glutaminyl Cyclase Inhibitor That Shows Activity in a Parkinson's Disease Mouse Model. J Med Chem. 2024 May 31.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-163655/Glutaminyl-Cyclase-Inhibitor-6-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-163655/
Clinical Information
No Development Reported
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