(R) -MK-8353
Product Specifications
Target
ERK
Related Pathways
MAPK
Bioactivity
(R) -MK-8353 ((R) -SCH900353) is the R-enantiomer of MK-8353. MK-8353 (SCH900353) is a potent, selective, orally active inhibitor of ERK1 and ERK2, with IC50 values of 23.0 nM and 8.8 nM, respectively.
Smiles
N(C(=O)[C@]1(SC)CN(CC(=O)N2CCC(=CC2)C3=CC=C(C=C3)C4=NN(C)C=N4)CC1)C=5C=C6C(=NNC6=CC5)C=7C=CC(OC(C)C)=NC7
Molecular Formula
C37H41N9O3S
Molecular Weight
691.85
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Product Datasheet
https://www.targetmol.com/attachment/DataSheet/390881299134988329/TYD-03994
CAS Number
2748457-30-7
Available Sizes
Curated Selection
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