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2-Methyl estradiol

Product Specifications

CAS Number

1818-12-8

Target

Endogenous Metabolite

Related Pathways

Metabolism

Bioactivity

2-Methyl estradiol is an endogenous metabolite of estradiol that inhibits cell proliferation and angiogenesis. The IC50 values for its effects on the proliferation of HUVEC (human umbilical vein endothelial cells) and MCF-7 (human breast cancer cells) are 3 μM and 2.39 μM, respectively.

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C[C@@]12[C@]([C@]3([C@@](C=4C(CC3)=CC(O)=C(C)C4)(CC1)[H])[H])(CC[C@@H]2O)[H]

Molecular Formula

C19H26O2

Molecular Weight

286.409

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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