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(−) -Voacangarine

Product Specifications

CAS Number

545-84-6

Target

Others|||Antifungal

Related Pathways

Others|||Microbiology/Virology

Bioactivity

(–) -Voacangarine, an indole alkaloid isolated from V. africana, exhibits cytotoxicity towards various cell lines including HepG2, A375, MDA-MB-231, SH-SY5Y, and CT26 with IC50 values of 20 µg/ml. Additionally, it demonstrates cytostatic effects on wild-type S. cerevisiae and is cytotoxic to ?rad3-e5 and ?rad6-1 mutant strains of S. cerevisiae, which have defects in DNA strand break repair and the mutagenic repair pathway, respectively.

Smiles

C(OC)(=O)[C@]12C3=C(C=4C(N3)=CC=C(OC)C4)CC[N@@]5[C@]1([C@@]([C@H](C)O)(C[C@](C2)(C5)[H])[H])[H]

Molecular Formula

C22H28N2O4

Molecular Weight

384.47

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

Curated Selection

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