P4HTM Protein, Human, Recombinant (His & SUMO)
Product Specifications
Bioactivity
Catalyzes the post-translational formation of 4-hydroxyproline in hypoxia-inducible factor (HIF) alpha proteins. Hydroxylates HIF1A at 'Pro-402' and 'Pro-564'. May function as a cellular oxygen sensor and, under normoxic conditions, may target HIF through the hydroxylation for proteasomal degradation via the von Hippel-Lindau ubiquitination complex.
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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