GBR-401
Product Specifications
CAS Number
1931954-95-8
Target
Immunology/Inflammation related
Related Pathways
Immunology/Inflammation
Bioactivity
GBR-401 is a humanized anti-CD19 monoclonal antibody with high affinity for Fc?RIIIa. It exhibits potent cytotoxicity in vitro and in vivo against various B-cell malignancies. GBR-401 induces cell death through antibody-dependent cellular cytotoxicity (ADCC) and direct cytotoxic effects. In severe combined immunodeficiency (SCID) mouse models with various xenografts, GBR-401 effectively eliminates malignant B cells and prolongs survival.
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
129632-ML650 100 µL
KXD1 (KxDL Motif-containing Protein 1, C19orf50, DKFZp686B1038, FLJ25480, FLJ43375, MGC2749, MST096, MSTP096, UPF0459 Protein C19orf50) (MaxLight 650)
Ask
View Details 
