AMT-562
Product Specifications
Target
EGFR, Apoptosis, Antibody-Drug Conjugates (ADCs), Topoisomerase
Related Pathways
Apoptosis, Antibody-drug Conjugate/ADC Related, Tyrosine Kinase/Adaptors, DNA Damage/DNA Repair, JAK/STAT signaling, Angiogenesis
Bioactivity
AMT-562 is an antibody-drug conjugate (ADC) composed of a novel anti-HER3 antibody, Ab562, linked to the linker Mc-VC-PAB and the topoisomerase I inhibitor, Exatecan. The ADC's toxic component and linker are represented as MC-VA-PAB-Exatecan. AMT-562 can induce apoptosis and exhibits antitumor activity against pancreatic, esophageal, and gastric cancers.
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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