PROTAC CYP1B1 degrader-2
Product Specifications
CAS Number
2836297-26-6
Target
PROTACs, Cytochromes P450
Related Pathways
Metabolism, PROTAC
Bioactivity
PROTAC CYP1B1 degrader-2 (compound PV2), a VHL (von Hippel - Landau) E3 ligase-based degrader of CYP1B1, exhibits a DC50 of 1.0 nM after 24 hours in A549/Taxol cells. Furthermore, it effectively inhibits the growth, migration, and invasion of A549/Taxol cells.
Smiles
O(CCCCCCCC(N[C@H](C(=O)N1[C@H](C(N[C@@H](C)C2=CC=C(C=C2)C=3SC=NC3C)=O)C[C@@H](O)C1)[C@@](C)(C)C)=O)C4=C(C=CC=C4)C=5N=C(SC5)C=6N=C(NC7=CC=C(Cl)C=C7)SC6
Molecular Formula
C49H56ClN7O5S3
Molecular Weight
954.66
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
BNC473348-500 1x 500 µL
NKX3.1 (Metastatic Prostate Adenocarcinoma Marker) (NKX3.1/3348), CF647 conjugate, 0.1mg/mL
Sign In for Pricing
View Details ![CD68 Mouse Monoclonal Antibody (HRP conjugated) [Clone ID: OTI10H10]](https://cdn.genprice.uk/products/937/68dd1b79061270361ea1b539/imageurl/ta802964bm.webp)
TA802964BM 100 µL
CD68 Mouse Monoclonal Antibody (HRP conjugated) [Clone ID: OTI10H10]
Sign In for Pricing
View Details 