Recombinant Human Ube2L6 Protein (His Tag)
Product Specifications
Background
Ubiquitin/ISG15-Conjugating Enzyme E2 L6 (UBE2L6) is an enzyme member of the E2 ubiquitin-conjugating enzyme family. UBE2L6 plays a same function as UBE2D; it catalyzes the covalent attachment of ubiquitin or ISG15 to other proteins. UBE2L6 promotes ubiquitination and subsequent proteasomal degradation of FLT3. It has functions in the E6/E6-AP-induced ubiquitination of p53/TP53.
Abbreviation
Ube2L6
Synonyms
RIG-B; Retinoic Acid-Induced Gene B Protein; UBCH8; UBE2L6; UbcH8; Ubiquitin Carrier Protein L6; Ubiquitin-Protein Ligase L6; Ubiquitin/ISG15-Conjugating Enzyme E2 L6
UniProt
O14933
Accession Number
O14933
Expression System
E.coli
Tag
C-His
Sequence
Met 1-Ser153
Field of Research
Epigenetics and Nuclear Signaling, Cell Biology
Endotoxin
< 1.0 EU per μg of the protein as determined by the LAL method.
Purity
> 95 % as determined by reducing SDS-PAGE.
Bioactivity
Not validated for activity
Reconstitution
Not Applicable
Shipping Conditions
This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C.
Storage Conditions
Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
Calculated Molecular Weight
18.8 kDa
Observed Molecular Weight
17 kDa
Formulation
Supplied as a 0.2 μm filtered solution of 50mM HEPES, 100mM NaCl, pH 8.0.
Species
Human
Available Sizes
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