EBET-1055
Product Specifications
Target
ADC Cytotoxin, PROTACs, Epigenetic Reader Domain
Related Pathways
Antibody-drug Conjugate/ADC Related, Chromatin/Epigenetic, PROTAC
Bioactivity
EBET-1055 is a degrader of bromodomain and extra-terminal (BET) proteins, consisting of a BET inhibitor (EBET-590), an E3 ubiquitin ligase ligand, and connectors. It effectively inhibits the growth of pancreatic ductal adenocarcinoma (PDAC) and also modulates cancer-associated fibroblast (CAF) activity, enhancing all reporter gene activities in organoid co-cultures [1].
Molecular Formula
C51H54N8O9
Molecular Weight
923.02
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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