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Triapine hydrochloride

Product Specifications

CAS Number

216240-62-9

Target

DNA/RNA Synthesis

Related Pathways

Cell Cycle/Checkpoint, DNA Damage/DNA Repair

Bioactivity

Triapine (hydrochloride), also known as 3-AP or PAN-811, represents the hydrochloride variant of Triapine. This compound serves as a potent inhibitor of the M2 subunit of ribonucleotide reductase (RR) and acts as an effective radiosensitizer [1].

Smiles

C(=NNC(N)=S)C1=C(N)C=CC=N1.Cl

Molecular Formula

C7H10ClN5S

Molecular Weight

231.71

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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