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HSD17B13-IN-36

Product Specifications

CAS Number

2730027-86-6

Target

Dehydrogenase

Related Pathways

Metabolism

Bioactivity

HSD17B13-IN-36 (compound 116) serves as a potent inhibitor of hydroxysteroid 17?-dehydrogenase 13 (HSD17B13), exhibiting an IC50 of <0.1 μM with estradiol as substrates. This compound is significant in the management of nonalcoholic fatty liver diseases (NAFLDs), including NASH (nonalcoholic steatohepatitis) [1].

Smiles

O(C1=NC(=NC=C1)C2=CC=C(C=C2)N3CCS(=O)(=O)CC3)C4=C(F)C(O)=C(F)C=C4

Molecular Formula

C20H17F2N3O4S

Molecular Weight

433.43

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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