ER-Tracker Blue-White DPX

ER-Tracker dye, a derivative of BODIPY series dyes coupled with Glibenclamide, exhibits high selectivity for the endoplasmic reticulum and is non-toxic to cells at low concentrations. This environmentally sensitive probe retains part of its fluorescence after formaldehyde treatment and features high fluorescence life and a good extinction coefficient. Glibenclamide, an ATP-dependent K+ channel blocker (Kir6, KATP) and CFTR Cl-channel blocker, binds in the endoplasmic reticulum. However, ER-Tracker is not suitable for staining cells after fixation [1].