Gly-Gly-Gly-PEG4-DBCO
This product is a cleavable linker for constructing antibody-drug conjugates (ADCs), featuring a Gly-Gly-Gly tripeptide and a tetraethylene glycol (PEG4) spacer terminated with a DBCO group. It enables site-specific conjugation via strain-promoted azide-alkyne cycloaddition (SPAAC) and is suitable for developing ADCs for both in vitro and in vivo cancer research applications.
Product Specifications
CAS Number
2353409-80-8
Product Name Alternative
ADC Linker, ADC linker, ADCLinker, Cleavable, Gly Gly Gly PEG4 DBCO, GlyGlyGlyPEG4DBCO, Gly-Gly-Gly-PEG-4-DBCO, Gly-Gly-Gly-PEG4-DBCO
Solubility
Methanol:50 mg/mL (71.97 mM) ; DMSO:80 mg/mL (115.15 mM)
Smiles
O=C (NCC (=O) NCC (=O) NCCOCCOCCOCCOCCNC (=O) CCC (=O) N1C=2C=CC=CC2C#CC=3C=CC=CC3C1) CN
Molecular Formula
C35H46N6O9
Molecular Weight
694.77
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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