Fmoc-VAP-MMAE
Product Specifications
CAS Number
1912408-91-3
Target
Drug-Linker Conjugates for ADC
Related Pathways
Antibody-drug Conjugate/ADC Related
Bioactivity
Fmoc-VAP-MMAE is a conjugate utilized in antibody-drug conjugates (ADCs), comprising a tubulin inhibitor, monomethyl auristatin E (MMAE), connected via an ADC linker, and shielded by a fluorenylmethyloxycarbonyl (Fmoc) protective group [1].
Smiles
C(OC(N[C@H](C(N[C@H](C(NC1=CC=C(COC(N([C@H](C(N[C@H](C(N([C@H]([C@@H](CC(=O)N2[C@]([C@@H]([C@H](C(N[C@@H]([C@@H](O)C3=CC=CC=C3)C)=O)C)OC)(CCC2)[H])OC)[C@H](CC)C)C)=O)C(C)C)=O)[C@@H](C)C)C)=O)C=C1)=O)C)=O)[C@@H](C)C)=O)C4C=5C(C=6C4=CC=CC6)=CC=CC5
Molecular Formula
C70H98N8O13
Molecular Weight
1259.57
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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