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QL-1200186

Product Specifications

CAS Number

2848664-42-4

Target

JAK

Related Pathways

JAK/STAT signaling|||Stem Cells|||Angiogenesis|||Chromatin/Epigenetic|||Tyrosine Kinase/Adaptors

Bioactivity

QL-1200186 is an orally active, selective TYK2 inhibitor that, upon dose-dependent oral administration, suppresses interferon-? (IFN?) production following interleukin-12 (IL-12) stimulation and markedly improves skin lesions in a psoriatic mouse model [1].

Smiles

O=C(NC)C1=CN=C2C=C1NC3=CC(=CC(C4=NN(C=C4)C)=C3OC)CCOCC5=NC(=CC=C5)N2

Molecular Formula

C26H27N7O3

Molecular Weight

485.54

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

Curated Selection

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