QL-1200186
Product Specifications
CAS Number
2848664-42-4
Target
JAK
Related Pathways
JAK/STAT signaling, Stem Cells, Angiogenesis, Chromatin/Epigenetic, Tyrosine Kinase/Adaptors
Bioactivity
QL-1200186 is an orally active, selective TYK2 inhibitor that, upon dose-dependent oral administration, suppresses interferon-γ (IFNγ) production following interleukin-12 (IL-12) stimulation and markedly improves skin lesions in a psoriatic mouse model [1].
Smiles
O=C(NC)C1=CN=C2C=C1NC3=CC(=CC(C4=NN(C=C4)C)=C3OC)CCOCC5=NC(=CC=C5)N2
Molecular Formula
C26H27N7O3
Molecular Weight
485.54
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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