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Propyl pyrazole triol (Standard)

Propyl pyrazole triol (Standard) is the analytical standard of Propyl pyrazole triol. This product is intended for research and analytical applications. Propyl pyrazole triol (PPT) is a selective estrogen receptor alpha (ERα) agonist. The relative binding affinity of Propyl pyrazole triol for ERα (ERα: 49%) around 410 times higher compared with estrogen receptor beta (ERβ: 0.12%) [1][2].

Product Specifications

CAS Number

263717-53-9

Product Name Alternative

PPT (Standard)

UNSPSC

12352005

Target

Estrogen Receptor/ERR; Reference Standards

Related Pathways

Others; Vitamin D Related/Nuclear Receptor

Field of Research

Cancer

Smiles

CCCC1=C(C2=CC=C(O)C=C2)N(C3=CC=C(O)C=C3)N=C1C4=CC=C(O)C=C4

Molecular Formula

C24H22N2O3

Molecular Weight

386.44

References & Citations

[1]Influence of cellular ERalpha/ERbeta ratio on the ERalpha-agonist induced proliferation of human T47D breast cancer cells.|[2]Stauffer SR, et al. Pyrazole ligands: structure-affinity/activity relationships and estrogen receptor-alpha-selective agonists. J Med Chem. 2000 Dec 28;43 (26) :4934-47.

Shipping Conditions

Room temperature

Scientific Category

Reference Standards

Frequently Asked Questions

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