Propyl pyrazole triol (Standard)
Propyl pyrazole triol (Standard) is the analytical standard of Propyl pyrazole triol. This product is intended for research and analytical applications. Propyl pyrazole triol (PPT) is a selective estrogen receptor alpha (ERα) agonist. The relative binding affinity of Propyl pyrazole triol for ERα (ERα: 49%) around 410 times higher compared with estrogen receptor beta (ERβ: 0.12%) [1][2].
Product Specifications
CAS Number
263717-53-9
Product Name Alternative
PPT (Standard)
UNSPSC
12352005
Target
Estrogen Receptor/ERR; Reference Standards
Related Pathways
Others; Vitamin D Related/Nuclear Receptor
Field of Research
Cancer
Smiles
CCCC1=C(C2=CC=C(O)C=C2)N(C3=CC=C(O)C=C3)N=C1C4=CC=C(O)C=C4
Molecular Formula
C24H22N2O3
Molecular Weight
386.44
References & Citations
[1]Influence of cellular ERalpha/ERbeta ratio on the ERalpha-agonist induced proliferation of human T47D breast cancer cells.|[2]Stauffer SR, et al. Pyrazole ligands: structure-affinity/activity relationships and estrogen receptor-alpha-selective agonists. J Med Chem. 2000 Dec 28;43 (26) :4934-47.
Shipping Conditions
Room temperature
Scientific Category
Reference Standards
Frequently Asked Questions
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