Sotuletinib dihydrochloride
Product Specifications
CAS Number
2222138-40-9
Target
C-Fms
Related Pathways
Tyrosine Kinase/Adaptors
Bioactivity
Sotuletinib (BLZ945) dihydrochloride is an orally administered, blood-brain barrier-permeable CSF1-R inhibitor with an IC50 of 1 nM, promoting apoptosis in tumor cells and significantly restricting tumor growth in murine models, thereby proving useful in cancer and amyotrophic lateral sclerosis (ALS) studies [1].
Smiles
N(C=1SC=2C(N1)=CC=C(OC=3C=C(C(NC)=O)N=CC3)C2)[C@H]4[C@H](O)CCCC4.Cl.Cl
Molecular Formula
C20H24Cl2N4O3S
Molecular Weight
471.4
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
![(-)-3,4,4a,5,6,10b-Hexahydro-2H-naphtho[1,2-b][1,4]oxazin-9-ol, Hydrochloride](https://cdn.genprice.uk/products/572/2348145790028/imageurl/trc-h294070-25mg.webp)
TRC-H294070-25MG 25 mg
(-)-3,4,4a,5,6,10b-Hexahydro-2H-naphtho[1,2-b][1,4]oxazin-9-ol, Hydrochloride
Sign In for Pricing
View Details 
BNUB1104-500 1x 500 µL
PAX2 (Renal Cell & Ovarian Carcinoma Marker) (PAX2/1104), 0.2mg/mL
Sign In for Pricing
View Details ![GDF15 Recombinant Rabbit Monoclonal Antibody [JE39-90]](https://cdn.genprice.uk/products/992/68dd1c8e061270361ea8235d/imageurl/ha722551.webp)
HA722551 100 µL
GDF15 Recombinant Rabbit Monoclonal Antibody [JE39-90]
Sign In for Pricing
View Details