GDF15 Recombinant Rabbit Monoclonal Antibody [JE39-90]

Growth/differentiation factor 15 is a protein that in humans is encoded by the GDF15 gene. GDF15 was first identified as Macrophage inhibitory cytokine-1 or MIC-1. It is a protein belonging to the transforming growth factor beta superfamily. Under normal conditions, GDF15 is expressed in low concentrations in most organs and upregulated because of injury of organs such as liver, kidney, heart and lung. The function of GDF15 is not fully clear but it seems to have a role in regulating inflammatory pathways and to be involved in regulating apoptosis, angiogenesis, cell repair and cell growth, which are biological processes observed in cardiovascular and neoplastic disorders.

Product Specifications

CAS Number

9000-83-3

Product Name Alternative

GDF 15 antibody GDF-15 antibody Gdf15 antibody GDF15_HUMAN antibody Growth differentiation factor 15 antibody Growth/differentiation factor 15 antibody Macrophage inhibitory cytokine 1 antibody MIC 1 antibody Mic-1 antibody MIC1 antibody NAG 1 antibody NAG-1 antibody NAG1 antibody NRG 1 antibody NRG-1 antibody NRG1 antibody NSAID (nonsteroidal anti inflammatory drug) activated protein 1 antibody NSAID antibody NSAID regulated protein 1 antibody NSAID-activated gene 1 protein antibody NSAID-regulated gene 1 protein antibody PDF antibody PLAB antibody Placental bone morphogenetic protein antibody Placental bone morphogenic protein antibody Placental TGF beta antibody Placental TGF-beta antibody Prostate differentiation factor antibody PTGF beta antibody PTGFB antibody

Abbreviation

GDF15, MIC1, PDF, PLAB, PTGFB

Swiss Prot

Q99988 Human

Cellular Locus

Secreted.

Host

Rabbit

Species Reactivity

Human

Immunogen

Recombinant protein within

Isotype

IgG

Clone

JE39-90

Conjugation

Non-conjugated

Type

Recombinant Rabbit monoclonal Antibody

Applications

Positive Control

HepG2 cell lysate, SK-MEL-28 cell lysate, LNCaP cell lysate.

Concentration

1 mg/mL

Dilution

WB: 1:2,000

Purity

Protein A affinity purified.

Form

Liquid

Buffer

1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

Molecular Weight

Predicted band size: 34 kDa

Storage Conditions

Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.

Recombinant Antibody

Yes

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