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LMTK3-IN-1

Product Specifications

CAS Number

2764850-23-7

Target

C-Met/HGFR

Related Pathways

Tyrosine Kinase/Adaptors

Purity

>99.99%

Bioactivity

Lmtk3-in-1 is a potent ATP-competitive lemur tyrosine kinase 3 (LMTK3) (Kd=2.5 μM) inhibitor that degrades LMTK3 through the ubiquitin proteasome pathway. LMTK3-IN-1 has shown anticancer activity in a variety of cancer cell lines and in vivo BC mouse models. LMTK3-IN-1 (10-20 μM) can induce the apoptosis of BC cell line.

Smiles

FC(F)(F)OC1=CC=CC(=C1)C2=CN=C3C=CC(=NN32)C=4C=CN=CC4

Molecular Formula

C18H11F3N4O

Molecular Weight

356.3

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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