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N, O-Didansyl-L-tyrosine cyclohexylammonium

Selected Variant

T77237-01

Size: 5 mg

Product Specifications

CAS Number

102783-47-1

Target

DNA/RNA Synthesis

Related Pathways

Cell Cycle/Checkpoint, DNA Damage/DNA Repair

Bioactivity

N, O-Didansyl-L-tyrosine cyclohexylammonium is a potent and selective inhibitor of thymidylate synthase (TS), showing activity against TS in Escherichia coli, Lactobacillus casei, and humans, with IC50 values of 5.0, 3.4, and 119 μM, respectively [1].

Smiles

NC1CCCCC1.CN(C)c1cccc2c(cccc12)S(=O)(=O)N[C@@H](Cc1ccc(OS(=O)(=O)c2cccc3c(cccc23)N(C)C)cc1)C(O)=O

Molecular Formula

C39H46N4O7S2

Molecular Weight

746.94

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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