Protein Kinase C β Peptide

Protein Kinase C (beta) Peptide, a fragment of Protein Kinase Cβ, is associated with hyperglycemia-induced decreases in endothelium-derived nitric oxide. Inhibiting Protein Kinase Cβ forestalls the impairment of endothelium-dependent vasodilation caused by acute hyperglycemia [1].

C([C@@H](NC([C@@H](NC(=O)[C@H]1N(C(CN)=O)CCC1)CCCCN)=O)[C@@H](C)O)(=O)N2[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@@H](CC3=CC=CC=C3)C(N[C@H](C(N[C@H](C(O)=O)CS)=O)CC(O)=O)=O)=O)CCCCN)=O)CO)=O)[C@H](CC)C)=O)[C@@H](C)O)=O)CC(N)=O)=O)C)=O)[C@@H](C)O)=O)CCCCN)=O)CCC(O)=O)=O)CCC(O)=O)=O)CCC2