What is the catalog number for RMC-6291?

The catalog number for RMC-6291 is T75131.

What sizes are available for RMC-6291?

RMC-6291 is available in the following size(s): 1 mg, 5 mg, 10 mg, 1 mL - 10 mM (in DMSO), 25 mg, 50 mg.

How many pack sizes does RMC-6291 come in?

RMC-6291 is available in 6 different pack sizes.

Is RMC-6291 in stock?

RMC-6291 is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures RMC-6291?

RMC-6291 is manufactured by Molfinity.

What is the estimated delivery time for RMC-6291?

Estimated delivery time for RMC-6291 is approximately 10 business day(s), depending on your location.

RMC-6291

Product Specifications

CAS Number

2641998-63-0

Target

Apoptosis, ERK, Ras, Kras

Related Pathways

MAPK, Apoptosis, GPCR/G Protein

Purity

0.9992

Bioactivity

RMC-6291 is an orally active, covalent inhibitor of KRAS G12C (ON) that forms a tri-complex within tumor cells between KRAS G12C (ON) and cyclophilin A (CypA), thereby preventing KRAS G12C (ON) from signaling via steric blockade of RAS effector binding and eliciting deep and durable suppression of RAS pathway activity in KRAS G12C tumor models [1].

Smiles

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