4?-Demethylnobiletin
Product Specifications
CAS Number
34810-62-3
Target
Others|||PKA|||ERK|||iGluR
Related Pathways
Tyrosine Kinase/Adaptors|||MAPK|||Neuroscience|||Membrane transporter/Ion channel|||Others
Bioactivity
4?-Demethylnobiletin, a bioactive metabolite, activates the PKA/ERK/CREB signaling pathway, enhances CRE-mediated transcription in hippocampal neurons, and reverses memory impairment linked to NMDA receptor antagonism through ERK signaling stimulation [1].
Smiles
COc1cc(ccc1O)-c1cc(=O)c2c(OC)c(OC)c(OC)c(OC)c2o1
Molecular Formula
C20H20O8
Molecular Weight
388.37
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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