PHF21A (NM_001101802) Human Recombinant Protein
Product Specifications
Background
The PHF21A gene encodes BHC80, a component of a BRAF35 (MIM 605535) /histone deacetylase (HDAC; see MIM 601241) complex (BHC) that mediates repression of neuron-specific genes through the cis-regulatory element known as repressor element-1 (RE1) or neural restrictive silencer (NRS) (Hakimi et al., 2002 [PubMed 12032298]) .[supplied by OMIM, Nov 2010]
Overview
Purified recombinant protein of Human PHD finger protein 21A (PHF21A), transcript variant 1, Pro445-End, with N-terminal His tag, expressed in E. coli, 50ug
Synonyms
BHC80; BM-006; IDDBCS; NEDMS
Gene ID
51317
UniProt
Q96BD5
Accession Number mRNA
NM_001101802
Chromosomal Location
11p11.2
Expression System
E. coli
Tag
N-His
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25mM Tris, pH8.0, 150 mM NaCl, 10% glycerol, 1% Sarkosyl.
Function
Druggable Genome, Transcription Factors
Molecular Weight
26 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
PHF21A
Species
Human
Protein ID
NP_001095272
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/51317
Uniprot URL
https://www.uniprot.org/uniprot/Q96BD5
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_001101802
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_001095272
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