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PROTAC Bcl-xL degrader-1

Product Specifications

Target

Others|||Bcl-2 Family|||PROTACs

Related Pathways

Apoptosis|||PROTAC|||Others

Bioactivity

PROTAC Bcl-xL degrader-1 is a potent PROTAC composed of a Bcl-xL (Bcl-2 family member) ligand-binding group, a linker, and an IAP E3 ligases binding group, demonstrating effectiveness as a Bcl-xL degrader. It exhibits toxicity towards human platelets and MyLa 1929 cells, with IC50 values of 62 nM and 8.5 ?M, respectively [1].

Molecular Formula

C76H96ClF3N10O11S3

Molecular Weight

1514.28

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

Curated Selection

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