Thiamine-d4 (hydrochloride)

Thiamine-d4 (hydrochloride) is deuterium labeled Thiamine (hydrochloride) . Thiamine hydrochloride (Thiamine chloride hydrochloride) is an essential micronutrient needed as a cofactor for many central metabolic enzymes.

Product Specifications

Product Name Alternative

Thiamine chloride-d4 (hydrochloride) ; Vitamin B1-d4 (hydrochloride)

UNSPSC

12352005

Target

Apoptosis; Endogenous Metabolite; HBV

Type

Isotope-Labeled Compounds

Related Pathways

Anti-infection; Apoptosis; Metabolic Enzyme/Protease

Applications

Neuroscience-Neurodegeneration

Field of Research

Neurological Disease

Purity

97.30

Solubility

10 mM in DMSO

Smiles

CC1=C(CC([2H])(O)[2H])SC=[N+]1C([2H])([2H])C2=CN=C(C)N=C2N.[H]Cl.[Cl-]

Molecular Formula

C12H14D4Cl2N4OS

Molecular Weight

341.29

References & Citations

[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53 (2) :211-216.|[2]Moulin M, et al. Analysis of Chlamydomonas thiamin metabolism in vivo reveals riboswitch plasticity. Proc Natl Acad Sci U S A. 2013 Sep 3;110 (36) :14622-7.