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NG-497

Product Specifications

CAS Number

2598242-66-9

Target

Lipase

Related Pathways

Metabolism

Purity

0.9957

Bioactivity

NG-497 is a selective, small molecule inhibitor of human adipose triglyceride lipase (ATGL) that targets the enzymatically active patatin-like structural domain of human ATGL.NG-497 binds ATGL in a hydrophobic lumen adjacent to the active site.NG-497 abrogates lipolysis in human adipocytes in a dose-dependent and reversible manner.NG-497 has been shown to be useful in cancer research. can be used in cancer research.

Smiles

C(OC(C)C)(=O)C1=NC(=CC(OC)=C1)C2=CC=C(OCC)C=C2

Molecular Formula

C18H21NO4

Molecular Weight

315.36

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

Curated Selection

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