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CD8B Antibody

This monoclonal antibody reacts with the mouse CD8 beta molecule. The CD8 beta chain associates with the CD8 alpha chain to form the CD8 alpha/beta heterodimer expressed on the surface of a majority of thymocytes, and on peripheral cytotoxic alpha beta TCR T cells. This monoclonal antibody identifies cytotoxic/suppressor T-cells that interact with MHC class I bearing targets. CD8 is thought to play a role in the process of T-cell mediated killing.

Product Specifications

UniProt

P10300

Host

Rat

Immunogen

Five day mixed leukocyte culture population, C57BL/6 anti-BALB/c

Clonality

Monoclonal

Isotype

IgG2b κ

Applications

Functional Studies, FACS, IF

Format

Purified

Buffer

0.2 mg/ml with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide

Reconstitution

Store the CD8b antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Limitations

This CD8b antibody is available for research use only.

CAS Number

9007-83-4

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