SAHA-OH
Product Specifications
CAS Number
2857098-30-5
Target
Apoptosis, HDAC
Related Pathways
DNA Damage/DNA Repair, Apoptosis, Chromatin/Epigenetic
Bioactivity
SAHA-OH, a selective HDAC6 inhibitor with an IC50 of 23 nM, exhibits a 10- to 47-fold greater selectivity for HDAC6 over HDACs 1, 2, 3, and 8. It demonstrates anti-inflammatory effects and reduces macrophage apoptosis [1].
Smiles
O=C(CCCCCCC(=O)NC1=CC=C(CO)C=C1)NO
Molecular Formula
C15H22N2O4
Molecular Weight
294.35
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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