EGFR/CDK2-IN-3

EGFR/CDK2-IN-3 is a potent dual inhibitor of EGFR (IC50 = 71.7 nM) and CDK2 (IC50 = 113.7 nM) . It demonstrates anti-proliferative activity in MCF-7 breast cancer cells (IC50 = 3.16 μM) by inducing S-phase cell cycle arrest and apoptosis, making it a useful chemical probe for oncology research.