Articaine
Product Specifications
CAS Number
23964-58-1
Target
Sodium Channel, Others, NOD-like Receptor (NLR), NF-κB
Related Pathways
Immunology/Inflammation, Others, NF-κB, Membrane transporter/Ion channel
Bioactivity
Articaine (Hoe-045 free base), an amide anesthetic featuring an ester group, effectively relieves pain by reversibly binding to the α-subunit of the voltage-gated sodium channels located in the nerve's inner cavity. Furthermore, Articaine mitigates LPS-induced acute kidney injury through the suppression of NF-κB activation and inhibition of the NLRP3 inflammasome pathway.
Smiles
CCCNC(C)C(=O)NC1=C(SC=C1C)C(=O)OC
Molecular Formula
C13H20N2O3S
Molecular Weight
284.37
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
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