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(S) -JDQ-443

Product Specifications

CAS Number

2653994-10-4

Target

Ras|||Others|||Kras|||PERK

Related Pathways

MAPK|||Others|||Apoptosis|||GPCR/G Protein

Bioactivity

(S) -JDQ-443 is an isomer of JDQ-443, which is an orally active, potent, selective, and covalent KRAS G12C inhibitor, showing antitumor activity [1] [2].

Smiles

CC1=C(C(=NN1C2CC3(C2)CN(C(C=C)=O)C3)C=4C=C5C(=CC4)N(C)N=C5)C6=C7C(=CC(C)=C6Cl)NN=C7

Molecular Formula

C29H28ClN7O

Molecular Weight

526.03

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

Curated Selection

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